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ORCIDAleksander S. Popel
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2020 – today
- 2024
[j18]Theinmozhi Arulraj
, Hanwen Wang, Alberto Ippolito, Shuming Zhang, Elana J. Fertig, Aleksander S. Popel:
Leveraging multi-omics data to empower quantitative systems pharmacology in immuno-oncology. Briefings Bioinform. 25(3) (2024)- [j17]Hanwen Wang, Theinmozhi Arulraj, Alberto Ippolito, Aleksander S. Popel:
From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling. npj Digit. Medicine 7(1) (2024) - 2022
- [j16]Alvaro Ruiz-Martinez, Chang Gong, Hanwen Wang, Richard J. Sové, Haoyang Mi, Holly Kimko, Aleksander S. Popel:
Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model. PLoS Comput. Biol. 18(7) (2022) - [j15]Zhenzhen Wang, Carla Saoud, Sintawat Wangsiricharoen, Aaron W. James, Aleksander S. Popel, Jeremias Sulam:
Label Cleaning Multiple Instance Learning: Refining Coarse Annotations on Single Whole-Slide Images. IEEE Trans. Medical Imaging 41(12): 3952-3968 (2022) - 2021
- [i1]Zhenzhen Wang, Aleksander S. Popel, Jeremias Sulam:
Label Cleaning Multiple Instance Learning: Refining Coarse Annotations on Single Whole-Slide Images. CoRR abs/2109.10778 (2021)
2010 – 2019
- 2019
- [j14]Chen Zhao, Adam C. Mirando, Richard J. Sové, Thalyta X. Medeiros, Brian H. Annex, Aleksander S. Popel:
A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology. PLoS Comput. Biol. 15(11) (2019) - 2017
- [j13]Kerri-Ann Norton, Travis Wallace, Niranjan B. Pandey, Aleksander S. Popel:
An agent-based model of triple-negative breast cancer: the interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia. BMC Syst. Biol. 11(1): 68:1-68:15 (2017) - [j12]Chen Zhao, Jeffrey S. Isenberg, Aleksander S. Popel:
Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model. PLoS Comput. Biol. 13(1) (2017) - [j11]Hojjat Bazzazi, Aleksander S. Popel:
Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells. PLoS Comput. Biol. 13(2) (2017) - 2015
- [j10]Chen Zhao, Aleksander S. Popel:
Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer. PLoS Comput. Biol. 11(11) (2015) - [c2]Polyxeni Gkontra, Magdalena M. Zak, Kerri-Ann Norton, Andrés Santos, Aleksander S. Popel, Alicia G. Arroyo:
A 3D Fractal-Based Approach towards Understanding Changes in the Infarcted Heart Microvasculature. MICCAI (3) 2015: 173-180 - 2011
- [j9]Prakash Vempati, Aleksander S. Popel, Feilim Mac Gabhann:
Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis. BMC Syst. Biol. 5: 59 (2011) - [j8]Stacey D. Finley, Marianne O. Engel-Stefanini, Princess I. Imoukhuede, Aleksander S. Popel:
Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies. BMC Syst. Biol. 5: 193 (2011)
2000 – 2009
- 2009
- [j7]Amina A. Qutub, Aleksander S. Popel:
Elongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sprouting. BMC Syst. Biol. 3: 13 (2009) - [j6]Marianne O. Stefanini, Florence T. H. Wu, Feilim Mac Gabhann, Aleksander S. Popel:
The Presence of VEGF Receptors on the Luminal Surface of Endothelial Cells Affects VEGF Distribution and VEGF Signaling. PLoS Comput. Biol. 5(12) (2009) - [c1]Amina A. Qutub, Gang Liu, Prakash Vempati, Aleksander S. Popel:
Integration of Angiogenesis Modules at Multiple Scales: From Molecular to Tissue. Pacific Symposium on Biocomputing 2009: 316-327 - 2008
- [j5]Marianne O. Stefanini, Florence T. H. Wu, Feilim Mac Gabhann, Aleksander S. Popel:
A compartment model of VEGF distribution in blood, healthy and diseased tissues. BMC Syst. Biol. 2: 77 (2008) - 2006
- [j4]Feilim Mac Gabhann, James W. Ji, Aleksander S. Popel:
Computational Model of Vascular Endothelial Growth Factor Spatial Distribution in Muscle and Pro-Angiogenic Cell Therapy. PLoS Comput. Biol. 2(9) (2006) - [j3]Feilim Mac Gabhann, Aleksander S. Popel:
Targeting Neuropilin-1 to Inhibit VEGF Signaling in Cancer: Comparison of Therapeutic Approaches. PLoS Comput. Biol. 2(12) (2006)
1990 – 1999
- 1999
- [j2]Kreg G. Gruben, Henry R. Halperin, Aleksander S. Popel, Joshua E. Tsitlik:
Canine sternal force-displacement relationship during cardiopulmonary resuscitation. IEEE Trans. Biomed. Eng. 46(7): 788-796 (1999) - 1990
- [j1]Isaac N. Bankman, Kreg G. Gruben, Henry R. Halperin, Aleksander S. Popel, Alan D. Guerci, Joshua E. Tsitlik:
Identification of dynamic mechanical parameters of the human chest during manual cadiopulmonary resuscitation. IEEE Trans. Biomed. Eng. 37(2): 211-217 (1990)
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